Table 1 of Chen, Mol Vis 2012; 18:816-829.


Table 1. Characteristics of the included studies

Author Year Ethnicity HWE PCV AMD Control Gene(s)/locus investigated Ref.
Gotoh 2004 Japanese yes 58 85 82 APOE [15]
Gotoh 2008 Japanese no 204 116 - HTRA1, CFH [35]
Gotoh 2009 Japanese yes 55 56 77 LOC387715 [24]
Gotoh 2010 Japanese yes 181 84 276 LOC387715, HTRA1 [25]
Yamashiro 2011 Japanese no 518 408 336 Elastin [20]
Yamashiro 2011 Japanese no 154 216 142 Elastin [20]
Nakanishi 2010 Japanese yes 375 - 847 LOC387715, CFH [26]
Hayashi 2010 Japanese yes 518 408 1351 LOC387715, CFH [27]
Nakata 2011 Japanese yes 167 - - PEDF, SERPINF1 [49]
Nakata 2011 Japanese yes 510 401 336 SERPING1 [37]
Tsujikawa 2011 Japanese no 88 - - LOC387715 [45]
Kondo 2007 Japanese yes 76 73 94 LOC387715, HTRA1 [16]
Kondo 2008 Japanese yes 103 78 104 Elastin [17]
Kondo 2009 Japanese yes 130 - 173 CFH [21]
Kondo 2009 Japanese yes 136 - 183 CFB, C2, RDBP, SKIV2L [21]
Kondo 2009 Japanese yes 140 116 189 SOD2 [40]
Bessho 2009 Japanese yes 140 116 189 PEDF [38]
Bessho 2011 Japanese no 119 68 - LOC387715 [34]
Sakurada 2008 Japanese yes 109 - 85 LOC387715 [30]
Sakurada 2009 Japanese yes 92 - - LOC387715 [44]
Sakurada 2010 Japanese yes 71 - - LOC387715 [18]
Sakurada 2011 Japanese yes 226 - - LOC387715, CFH [23]
Goto 2009 Japanese yes 100 100 190 LOC387715, CFH, C3 [29]
Fuse 2011 Japanese yes 60 50 138 LOC387715, LOXL1 [28]
Tanaka 2011 Japanese yes 287 - 277 LOC387715, CFH [31]
Park 2011 Korea yes 103 - 112 LOC387715, HTRA1 [33]
Park 2011 Korea yes 51 -
LOC387715, HTRA1 [43]
Li 2010 Chinese yes 118 - 115 SERPING1 [36]
Zhang 2011 Chinese yes 177 131 182 9p21 [42]
Wu 2011 Chinese yes 177 131 182 PEDF [39]
Sng 2011 Chinese yes 120 126 274 Toll-like receptor 3 [41]
Lee 2008 Chinese yes 72 - 93 LOC387715, CFH, CFB, C2 [32]
Lima 2011 Caucasian no 56 368 368 Elastin [19]
Lima 2010 Caucasian no 55 368 368 LOC387715, CFH, CFB, C2 [22]