Table 2 of Riemens, Mol Vis 2012; 18:797-802.

Table 2. Inflammatory cytokines in tear fluid and ocular findings after allo-ACT.


Inflammatory
cytokines and
ocular findings
Allo-SCT
patients
(n=34)		 Ocular
GvHD
patients
(n=16)		 No ocular
GvHD
patients
(n=18)
Healthy
Controls
(n=16)		 p-value,
Ocular
GvHD versus
No Ocular GvHD		 p-value,
Ocular GvHD
versus
Healthy Controls		 p-value,
No Ocular
GvHD versus
Healthy Controls
IL-6, pg/ml, n (%) 15/34 (44%) 11/16 (69%) 4/18 (22%) 1/16 (6%) p=0.005 p<0.0001 NS
Median, iq range 0, 130.6 107.4, 417.1 0, 7.9 0, 0      
IFN-γ, pg/ml, n (%) 8/34 (23%) 8/16 (50%) 0/18 (0%) 0/16 (0%) p=0.001 p=0.002 NA
Median, iq range 0, 0 572, 1372.9 0, 0        
Mean Schirmer ±SD, mm 10.7±8.2 mm 4.4±2.0 mm 16.2±7.5 mm 22.1±7 mm p<0.0001 p<0.0001 p=0.021
Median OSDI score, iq range 11.1, 14.0 13.9, 21.21) 6.0, 27.82) 0, 3.7 p=0.015 p<0.0001 p=0.026

Allo-SCT, allogeneic stem cell transplantation; n, Number of patients; GvHD, Graft-versus-Host-Disease; IFN- γ, interferon- γ; IL-6, interleukin-6; Iq range, Interquartile range; OSDI, Ocular Surface Disease Index; NS=Not statistically significant NA, Not Applicable; SD, Standard Deviation; 1) Data from 1 patient is missing; 2) Data from 2 patients is missing.

Riemens, Mol Vis 2012; 18:797-802. http://www.molvis.org/molvis/v18/a85

©2012 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535