Table 4 of Chen, Mol Vis 2012; 18:765-778.


Table 4. Association of GJD2rs634990, IGF1rs6214, and HGFrs3735520 with axial ocular dimensions.

    STM NAI Meta-analysis
Gene SNP β SEM p* β SEM p β SEM p Adjusted p
Axial length
GJD2 rs634990 0.052 0.124 0.678 −0.042 0.070 0.544 −0.019 0.061 0.752 0.985
IGF1 rs6214 0.091 0.121 0.452 −0.009 0.066 0.896 0.014 0.058 0.810 0.993
HGF rs3735520 0.347 0.126 0.006 0.015 0.069 0.831 0.092 0.061 0.130 0.342
Central corneal thickness
GJD2 rs634990 −9.386 3.517 0.008 0.819 2.131 0.701 −1.922 1.823 0.292 0.645
IGF1 rs6214 −3.054 3.452 0.377 −1.454 2.015 0.471 −1.861 1.740 0.285 0.634
HGF rs3735520 −2.180 3.674 0.553 2.245 2.104 0.287 1.152 1.826 0.528 0.895
Anterior chamber depth
GJD2 rs634990 0.005 0.030 0.865 −0.024 0.022 0.276 −0.014 0.018 0.435 0.819
IGF1 rs6214 −0.011 0.029 0.709 −0.008 0.020 0.699 −0.009 0.017 0.586 0.929
HGF rs3735520 0.002 0.031 0.937 −0.013 0.021 0.554 −0.008 0.017 0.634 0.951
Lens thickness
GJD2 rs634990 0.018 0.042 0.674 −0.002 0.028 0.935 0.004 0.023 0.859 0.997
IGF1 rs6214 0.049 0.041 0.240 0.058 0.026 0.027 0.055 0.022 0.012 0.034
HGF rs3735520 0.018 0.044 0.687 −0.044 0.027 0.113 −0.027 0.023 0.240 0.561
Vitreous chamber depth
GJD2 rs634990 −0.006 0.117 0.963 −0.030 0.070 0.669 −0.024 0.060 0.694 0.971
IGF1 rs6214 0.021 0.114 0.854 −0.044 0.066 0.506 −0.028 0.057 0.628 0.948
HGF rs3735520 0.348 0.120 0.004 0.075 0.069 0.277 0.143 0.060 0.017 0.050