Table 4 of Chen, Mol Vis 2012; 18:765-778.
STM | NAI | Meta-analysis | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Gene | SNP | β | SEM | p* | β | SEM | p | β | SEM | p | Adjusted p |
Axial length | |||||||||||
GJD2 | rs634990 | 0.052 | 0.124 | 0.678 | −0.042 | 0.070 | 0.544 | −0.019 | 0.061 | 0.752 | 0.985 |
IGF1 | rs6214 | 0.091 | 0.121 | 0.452 | −0.009 | 0.066 | 0.896 | 0.014 | 0.058 | 0.810 | 0.993 |
HGF | rs3735520 | 0.347 | 0.126 | 0.006 | 0.015 | 0.069 | 0.831 | 0.092 | 0.061 | 0.130 | 0.342 |
Central corneal thickness | |||||||||||
GJD2 | rs634990 | −9.386 | 3.517 | 0.008 | 0.819 | 2.131 | 0.701 | −1.922 | 1.823 | 0.292 | 0.645 |
IGF1 | rs6214 | −3.054 | 3.452 | 0.377 | −1.454 | 2.015 | 0.471 | −1.861 | 1.740 | 0.285 | 0.634 |
HGF | rs3735520 | −2.180 | 3.674 | 0.553 | 2.245 | 2.104 | 0.287 | 1.152 | 1.826 | 0.528 | 0.895 |
Anterior chamber depth | |||||||||||
GJD2 | rs634990 | 0.005 | 0.030 | 0.865 | −0.024 | 0.022 | 0.276 | −0.014 | 0.018 | 0.435 | 0.819 |
IGF1 | rs6214 | −0.011 | 0.029 | 0.709 | −0.008 | 0.020 | 0.699 | −0.009 | 0.017 | 0.586 | 0.929 |
HGF | rs3735520 | 0.002 | 0.031 | 0.937 | −0.013 | 0.021 | 0.554 | −0.008 | 0.017 | 0.634 | 0.951 |
Lens thickness | |||||||||||
GJD2 | rs634990 | 0.018 | 0.042 | 0.674 | −0.002 | 0.028 | 0.935 | 0.004 | 0.023 | 0.859 | 0.997 |
IGF1 | rs6214 | 0.049 | 0.041 | 0.240 | 0.058 | 0.026 | 0.027 | 0.055 | 0.022 | 0.012 | 0.034 |
HGF | rs3735520 | 0.018 | 0.044 | 0.687 | −0.044 | 0.027 | 0.113 | −0.027 | 0.023 | 0.240 | 0.561 |
Vitreous chamber depth | |||||||||||
GJD2 | rs634990 | −0.006 | 0.117 | 0.963 | −0.030 | 0.070 | 0.669 | −0.024 | 0.060 | 0.694 | 0.971 |
IGF1 | rs6214 | 0.021 | 0.114 | 0.854 | −0.044 | 0.066 | 0.506 | −0.028 | 0.057 | 0.628 | 0.948 |
HGF | rs3735520 | 0.348 | 0.120 | 0.004 | 0.075 | 0.069 | 0.277 | 0.143 | 0.060 | 0.017 | 0.050 |