Figure 4 of Montalbán-Soler, Mol Vis 2012; 18:675-693.

Figure 4. Phototoxicity induces apoptotic photoreceptor death. Merged images (Adobe® Photoshop® CS3, “dissolve” option) showing the TdT-mediated dUTP nick-end labeling (TUNEL)-positive (red) and 4',6-diamidino-2-phenylindole (DAPI)-counterstained (blue) nuclei in retinal cross sections from the dorsal (left column) and ventral (right column) central retinas. A, B: control animals; C-J: experimental animals processed at increasing times ALE. C, D: 1 day; E, F: 3 days; G, H: 7 days and I, J: 14 days. TUNEL positive nuclei are observed in the ONL (mainly in the dorsal retina) of the experimental animals processed 1, 3 and 7 days ALE, but not thereafter. Abbreviations: RGCL: retinal ganglion cell layer, IPL: inner plexiform layer, INL: inner nuclear layer, OPL: outer plexiform layer, ONL: outer nuclear layer, OSPL: outer segment of photoreceptors layer. Bar=100 μm.