Table 2 of Baas, Mol Vis 2012; 18:657-674.


Table 2. Odds Ratios (OR) and 95% confidence intervals (CI) of AMD cases versus controls of the AMRO-NL study population for three SNPs in SLC2A1

  No AMD All AMD cases Early AMD Late AMD
  n=179 n=358 n=91 n=267
rs3754219 No. (%) No. (%) OR (95%CI) No. (%) OR (95%CI) No. (%) OR (95%CI)
Genotype
Noncarrier (AA) 44 (24.6) 118 (33.0) 1 23 (25.3) 1 95 (35.6) 1
Heterozygous (Aa) 84 (46.9) 184 (51.4) 0.82 (0.53–1.27) 52 (57.1) 1.32 (0.72–2.43) 132 (49.4) 0.73 (0.46–1.14)
Homozygous (aa) 51 (28.5) 56 (28.5) 0.44 (0.26–0.74) 16 (17.6) 0.59 (0.28–1.27) 40 (15.0) 0.37 (0.21–0.66)
m.a.f (%) 51.9 41.3   46.2   39.7  
   n=150 n=279 n=82 n=197
rs4660687 No. (%) No. (%) OR (95%CI) No. (%) OR (95%CI) No. (%) OR (95%CI)
Genotype
Noncarrier (AA) 71 (47.3) 95 (34.1) 1 24 (29.3) 1 71 (36.0) 1
Heterozygous (Aa) 57 (38.0) 133 (47.7) 1.74 (1.13–2.70) 41 (50.0) 2.13 (1.15–3.93) 92 (46.7) 1.61 (1.01–2.57)
Homozygous (aa) 22 (14.7) 51 (18.3) 1.73 (0.96–3.12) 17 (20.7) 2.29 (1.04–5.01) 34 (17.3) 1.55 (0.82–2.90)
m.a.f (%) 33.7 42.1   45.7   40.6  
  n=179 n=359 n=91 n=268
rs841853 No. (%) No. (%) OR (95%CI) No. (%) OR (95%CI) No. (%) OR (95%CI)
Genotype
Noncarrier (AA) 104 (58.1) 150 (41.8) 1 47 (51.6) 1 103 (38.4) 1
Heterozygous (Aa) 62 (34.6) 168 (47.0) 1.87 (1.27–2.77) 37 (40.7) 1.44 (0.84–2.46) 131 (48.9) 2.21 (1.42–3.39)
Homozygous (aa) 13 (7.3) 41 (11.4) 2.24 (1.13–4.41) 7 (7.7) 1.32 (0.49–3.55) 34 (12.7) 2.64 (1.28–5.46)
m.a.f (%) 24.6 34.9   28   37.1