Table 2 of
Baas, Mol Vis 2012; 18:657-674. Table 2 of
Baas, Mol Vis 2012; 18:657-674.
Table 2. Odds Ratios (OR) and 95% confidence intervals (CI) of AMD cases versus controls of the AMRO-NL study population for three SNPs in SLC2A1
| No AMD | All AMD cases | Early AMD | Late AMD | ||||
|---|---|---|---|---|---|---|---|
| n=179 | n=358 | n=91 | n=267 | ||||
| rs3754219 | No. (%) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) |
| Genotype | |||||||
| Noncarrier (AA) | 44 (24.6) | 118 (33.0) | 1 | 23 (25.3) | 1 | 95 (35.6) | 1 |
| Heterozygous (Aa) | 84 (46.9) | 184 (51.4) | 0.82 (0.53–1.27) | 52 (57.1) | 1.32 (0.72–2.43) | 132 (49.4) | 0.73 (0.46–1.14) |
| Homozygous (aa) | 51 (28.5) | 56 (28.5) | 0.44 (0.26–0.74) | 16 (17.6) | 0.59 (0.28–1.27) | 40 (15.0) | 0.37 (0.21–0.66) |
| m.a.f (%) | 51.9 | 41.3 | 46.2 | 39.7 | |||
| n=150 | n=279 | n=82 | n=197 | ||||
| rs4660687 | No. (%) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) |
| Genotype | |||||||
| Noncarrier (AA) | 71 (47.3) | 95 (34.1) | 1 | 24 (29.3) | 1 | 71 (36.0) | 1 |
| Heterozygous (Aa) | 57 (38.0) | 133 (47.7) | 1.74 (1.13–2.70) | 41 (50.0) | 2.13 (1.15–3.93) | 92 (46.7) | 1.61 (1.01–2.57) |
| Homozygous (aa) | 22 (14.7) | 51 (18.3) | 1.73 (0.96–3.12) | 17 (20.7) | 2.29 (1.04–5.01) | 34 (17.3) | 1.55 (0.82–2.90) |
| m.a.f (%) | 33.7 | 42.1 | 45.7 | 40.6 | |||
| n=179 | n=359 | n=91 | n=268 | ||||
| rs841853 | No. (%) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) | No. (%) | OR (95%CI) |
| Genotype | |||||||
| Noncarrier (AA) | 104 (58.1) | 150 (41.8) | 1 | 47 (51.6) | 1 | 103 (38.4) | 1 |
| Heterozygous (Aa) | 62 (34.6) | 168 (47.0) | 1.87 (1.27–2.77) | 37 (40.7) | 1.44 (0.84–2.46) | 131 (48.9) | 2.21 (1.42–3.39) |
| Homozygous (aa) | 13 (7.3) | 41 (11.4) | 2.24 (1.13–4.41) | 7 (7.7) | 1.32 (0.49–3.55) | 34 (12.7) | 2.64 (1.28–5.46) |
| m.a.f (%) | 24.6 | 34.9 | 28 | 37.1 | |||