Table 1 of Baas, Mol Vis 2012; 18:657-674.


Table 1. Allelic association between age-related macular degeneration and 22 selected SLC2A1 single nucleotide polymorphisms in the AMRO-NL study population

No AMD (controls) AMD (cases)
SNP ID AA number (%) Aa number (%) aa number (%) m.a.f AA number (%) Aa number (%) aa number (%) m.a.f Allelic p-value HWE
rs1105297 94 (51.4) 75 (41.0) 14 (7.7) 28.1 171 (47.2) 159 (43.9) 32 (8.8) 30.8 0.3652 yes
rs1770810 115 (62.8) 59 (32.2) 9 (4.9) 21 232 (64.4) 117 (32.5) 11 (3.1) 19.3 0.5203 yes
rs1770811 109 (59.9) 64 (33.7) 9 (4.9) 22.5 229 (63.3) 122 (33.7) 11 (3.0) 19.9 0.3419 yes
rs12407920 161 (89.9) 16 (8.9) 2 (1.1) 5.5 293 (82.1) 64 (17.9) 0 (0.0) 9 0.0538 no
rs16830101 161 (89.9) 16 (8.9) 2 (1.1) 5.5 292 (82.0) 64 (18.0) 0 (0.0) 9 0.0509 no
rs3754219 44 (24.6) 84 (46.9) 51 (28.5) 52 118 (33.0) 184 (51.4) 56 (15.6) 41.3 0.0011 yes
rs3754223 108 (59.7) 67 (37.0) 6 (3.3) 21.8 225 (62.2) 124 (34.3) 13 (3.6) 20.7 0.6935 yes
rs3768043 108 (59.0) 68 (37.2) 7 (3.8) 22.4 219 (60.5) 129 (35.6) 14 (3.9) 21.7 0.8162 yes
rs4660687 71 (47.3) 57 (38.0) 22 (14.7) 33.7 95 (34.1) 133 (47.7) 51 (18.3) 42.1 0.0157 yes
rs4660691 109 (59.6) 68 (37.2) 6 (3.3) 21.9 224 (62.0) 124 (34.3) 13 (3.6) 20.8 0.6947 yes
rs710221 64 (35.0) 96 (52.5) 23 (12.6) 38.8 106 (29.4) 193 (53.6) 61 (16.9) 43.8 0.1193 yes
rs710222 64 (35.2) 96 (52.7) 22 (12.1) 38.5 108 (29.8) 193 (53.3) 61 (16.9) 43.5 0.1182 yes
rs751210 94 (51.4) 75 (41.0) 14 (7.7) 28.1 170 (47.2) 158 (43.9) 32 (8.9) 30.8 0.4003 yes
rs841845 114 (62.3) 60 (32.8) 9 (4.9) 21.3 231 (64.0) 119 (33.0) 11 (3.0) 19.5 0.5222 yes
rs841848 114 (62.3) 60 (32.8) 9 (4.9) 21.3 230 (63.5) 121 (33.4) 11 (3.0) 19.8 0.5767 yes
rs841851 114 (62.3) 60 (32.8) 9 (4.9) 21.3 232 (64.1) 119 (33.0) 11 (3.0) 19.5 0.4725 yes
rs841852 114 (62.3) 60 (32.8) 9 (4.9) 21.3 231 (64.0) 119 (33.0) 11 (3.0) 19.5 0.5222 yes
rs841853 104 (58.1) 62 (34.6) 13 (7.3) 24.6 150 (41.8) 168 (47.0) 41 (11.4) 34.9 0.0006 yes
rs841856 113 (61.7) 61 (33.3) 9 (4.9) 21.6 227 (63.4) 120 (33.5) 11 (3.1) 19.8 0.524 yes
rs841858 129 (70.5) 47 (25.7) 7 (3.8) 16.7 250 (69.3) 102 (28.3) 9 (2.5) 16.6 1 yes
rs900836 109 (59.6) 68 (37.2) 6 (3.3) 21.9 224 (62.0) 124 (34.3) 13 (3.6) 20.8 0.6947 yes
rs900837 109 (59.6) 68 (37.2) 6 (3.3) 21.9 224 (62.0) 124 (34.3) 13 (3.6) 20.8 0.6947 yes