Table 1 of
Baas, Mol Vis 2012; 18:657-674. Table 1 of
Baas, Mol Vis 2012; 18:657-674.
Table 1. Allelic association between age-related macular degeneration and 22 selected SLC2A1 single nucleotide polymorphisms in the AMRO-NL study population
| No AMD (controls) | AMD (cases) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| SNP ID | AA number (%) | Aa number (%) | aa number (%) | m.a.f | AA number (%) | Aa number (%) | aa number (%) | m.a.f | Allelic p-value | HWE |
| rs1105297 | 94 (51.4) | 75 (41.0) | 14 (7.7) | 28.1 | 171 (47.2) | 159 (43.9) | 32 (8.8) | 30.8 | 0.3652 | yes |
| rs1770810 | 115 (62.8) | 59 (32.2) | 9 (4.9) | 21 | 232 (64.4) | 117 (32.5) | 11 (3.1) | 19.3 | 0.5203 | yes |
| rs1770811 | 109 (59.9) | 64 (33.7) | 9 (4.9) | 22.5 | 229 (63.3) | 122 (33.7) | 11 (3.0) | 19.9 | 0.3419 | yes |
| rs12407920 | 161 (89.9) | 16 (8.9) | 2 (1.1) | 5.5 | 293 (82.1) | 64 (17.9) | 0 (0.0) | 9 | 0.0538 | no |
| rs16830101 | 161 (89.9) | 16 (8.9) | 2 (1.1) | 5.5 | 292 (82.0) | 64 (18.0) | 0 (0.0) | 9 | 0.0509 | no |
| rs3754219 | 44 (24.6) | 84 (46.9) | 51 (28.5) | 52 | 118 (33.0) | 184 (51.4) | 56 (15.6) | 41.3 | 0.0011 | yes |
| rs3754223 | 108 (59.7) | 67 (37.0) | 6 (3.3) | 21.8 | 225 (62.2) | 124 (34.3) | 13 (3.6) | 20.7 | 0.6935 | yes |
| rs3768043 | 108 (59.0) | 68 (37.2) | 7 (3.8) | 22.4 | 219 (60.5) | 129 (35.6) | 14 (3.9) | 21.7 | 0.8162 | yes |
| rs4660687 | 71 (47.3) | 57 (38.0) | 22 (14.7) | 33.7 | 95 (34.1) | 133 (47.7) | 51 (18.3) | 42.1 | 0.0157 | yes |
| rs4660691 | 109 (59.6) | 68 (37.2) | 6 (3.3) | 21.9 | 224 (62.0) | 124 (34.3) | 13 (3.6) | 20.8 | 0.6947 | yes |
| rs710221 | 64 (35.0) | 96 (52.5) | 23 (12.6) | 38.8 | 106 (29.4) | 193 (53.6) | 61 (16.9) | 43.8 | 0.1193 | yes |
| rs710222 | 64 (35.2) | 96 (52.7) | 22 (12.1) | 38.5 | 108 (29.8) | 193 (53.3) | 61 (16.9) | 43.5 | 0.1182 | yes |
| rs751210 | 94 (51.4) | 75 (41.0) | 14 (7.7) | 28.1 | 170 (47.2) | 158 (43.9) | 32 (8.9) | 30.8 | 0.4003 | yes |
| rs841845 | 114 (62.3) | 60 (32.8) | 9 (4.9) | 21.3 | 231 (64.0) | 119 (33.0) | 11 (3.0) | 19.5 | 0.5222 | yes |
| rs841848 | 114 (62.3) | 60 (32.8) | 9 (4.9) | 21.3 | 230 (63.5) | 121 (33.4) | 11 (3.0) | 19.8 | 0.5767 | yes |
| rs841851 | 114 (62.3) | 60 (32.8) | 9 (4.9) | 21.3 | 232 (64.1) | 119 (33.0) | 11 (3.0) | 19.5 | 0.4725 | yes |
| rs841852 | 114 (62.3) | 60 (32.8) | 9 (4.9) | 21.3 | 231 (64.0) | 119 (33.0) | 11 (3.0) | 19.5 | 0.5222 | yes |
| rs841853 | 104 (58.1) | 62 (34.6) | 13 (7.3) | 24.6 | 150 (41.8) | 168 (47.0) | 41 (11.4) | 34.9 | 0.0006 | yes |
| rs841856 | 113 (61.7) | 61 (33.3) | 9 (4.9) | 21.6 | 227 (63.4) | 120 (33.5) | 11 (3.1) | 19.8 | 0.524 | yes |
| rs841858 | 129 (70.5) | 47 (25.7) | 7 (3.8) | 16.7 | 250 (69.3) | 102 (28.3) | 9 (2.5) | 16.6 | 1 | yes |
| rs900836 | 109 (59.6) | 68 (37.2) | 6 (3.3) | 21.9 | 224 (62.0) | 124 (34.3) | 13 (3.6) | 20.8 | 0.6947 | yes |
| rs900837 | 109 (59.6) | 68 (37.2) | 6 (3.3) | 21.9 | 224 (62.0) | 124 (34.3) | 13 (3.6) | 20.8 | 0.6947 | yes |