Table 3 of Ha, Mol Vis 2012; 18:645-656.


Table 3. Summary of candidate Wnt target gene validation.

        qPCR validation  
Gene Fold-change on microarray # TCF binding sites # conserved sites Explants β-catAct in situ β-catAct
Wnt pathway
Wif1 29.2 7 1 + + +
Axin2 2.8 6 4 + + nd
Ciliary margin markers
Msx1 2.3 6 3 nd nd +
Otx1 1.8 9 7 nd nd +
Neuron development
Epha2 8.4 4 1 - - nd
Efna3 1.7 4 1 + - nd
Syt13 −11 6 0 + - +
Prickle1 −6 9 1 + - nd
Ndrg2 −2.8 4 2 + - nd
Cell cycle
Cdkn1a 21.9* 3 0 + + +
Differentiation
Serpine2 25.1 1 1 + - nd
Klf10 2.3 1 0 + - nd
Cdc25b 1.9 4 1 + - nd
Lix1 2.5** 12 4 - + -
Signaling
Tnfrsf19 20.9 10 2 + + +
Med12 2 8 0 - - -