Table 7 of Zhuang, Mol Vis 2012; 18:634-644.

Table 7. Haplotype analysis of IGF-1 in extreme myopia and control subjects.


Block
Haplotype		 Freq of
case (%)		 Freq of
control (%)
p value*		 OR
(95%CI)
P-permutation**
Block 1
(rs10860862-rs6214) GG 46.5 49.7 0.232 1 0.7773
  GA 37.0 32.7 0.098 1.209 (0.956–1.529) 0.4638
  TA 16.5 17.4 0.661 1.014 (0.752–1.367) 0.9977
Block 2
(rs5742629-rs12423791) AG 56.5 62.3 0.026 1 0.1541
  GC 29.6 22.9 0.005 1.426 (1.114–1.827) 0.0334
  GG 13.9 14.7 0.670 1.044 (0.764–1.426) 0.9981
Block 3
(rs35766-rs1457601) GA 66.1 71.1 0.042 1 0.2409
  AT 27.5 22.6 0.037 1.308 (1.002–1.673) 0.2138
  AA 6.5 6.2 0.875 1.112 (0.718–1.723) 1.0000

The asterisk indicates that differences in the estimated haplotype frequency were examined by the χ2 test. The double asterisk indicates that 50,000 permutations were performed. OR indicates odds ratio and CI indicates confidence interval which were performed by a logistic regression model.

Zhuang, Mol Vis 2012; 18:634-644. http://www.molvis.org/molvis/v18/a70

©2012 Molecular Vision http://www.molvis.org/molvis/

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