Table 4 of
Zhuang, Mol Vis 2012; 18:634-644.
Table 4. Haplotype analysis of the IGF-1 gene in high myopia and control subjects.
Block |
Haplotype |
Freq of case (%) |
Freq of control (%) |
p value* |
OR (95%CI) |
P-permutation** |
---|---|---|---|---|---|---|
Block 1 | ||||||
(rs10860862-rs6214) | GG | 47.9 | 49.8 | 0.444 | 1 | 0.9620 |
GA | 35.9 | 32.8 | 0.184 | 1.138 (0.917–1.413) | 0.6928 | |
TA | 16.3 | 17.5 | 0.506 | 0.966 (0.735–1.270) | 0.9826 | |
Block 2 | ||||||
(rs5742629-rs12423791) | AG | 56.8 | 62.3 | 0.021 | 1 | 0.1346 |
GC | 27.8 | 22.9 | 0.024 | 1.330 (1.057–1.675) | 0.1436 | |
GG | 15.4 | 14.7 | 0.681 | 1.152 (0.872–1.523) | 0.9986 | |
Block 3 | ||||||
(rs35766-rs1457601) | AT | 67.3 | 71.1 | 0.010 | 1 | 0.4510 |
GA | 27.1 | 22.6 | 0.037 | 1.264 (1.007–1.586) | 0.2109 | |
GT | 5.6 | 6.2 | 0.566 | 0.943 (0.623–1.428) | 0.9894 |