Table 2 of
Zhuang, Mol Vis 2012; 18:634-644. Table 2 of
Zhuang, Mol Vis 2012; 18:634-644.
Table 2. The genotype distribution and allelic frequencies of polymorphisms in high myopia and control subjects.
| RefSNP ID | Genotype | Cases | Controls | OR (95% CI) | p-value | Allele | Cases | Controls | OR (95% CI) | p-value |
|---|---|---|---|---|---|---|---|---|---|---|
| n (%) | 421 | 401 | n (%) | 842 | 802 | |||||
| rs10860861 | T/T | 153 (36.3) | 138 (34.4) | 1 | 0.840 | T | 508 (60.3) | 473 (59.0) | 1 | 0.576 |
| T/C | 202 (48.0) | 197 (49.1) | 0.902 (0.598–1.361) | C | 334 (39.7) | 329 (41.0) | 0.945 (0.776–1.151) | |||
| C/C | 66 (15.7) | 66 (16.5) | 0.975 (0.658–1.446) | |||||||
| HWE-p | 0.96 | 0.76 | ||||||||
| rs10860862 | G/G | 294 (69.8) | 272 (67.8) | 1 | 0.759 | G | 705 (83.7) | 661 (82.4) | 1 | 0.479 |
| G/T | 117 (27.8) | 117 (29.2) | 0.771 (0.328–1.813) | T | 137 (16.3) | 141 (17.6) | 0.911 (0.704–1.179) | |||
| T/T | 10 (2.4) | 12 (3.0) | 0.833 (0.347–2.004) | |||||||
| HWE-p | 0.68 | 0.89 | ||||||||
| rs6214 | G/G | 99 (23.5) | 100 (24.9) | 1 | 0.686 | G | 403 (47.9) | 400 (49.9) | 1 | 0.414 |
| G/A | 205 (48.7) | 200 (49.9) | 1.170 (0.796–1.719) | A | 439 (52.1) | 402 (50.1) | 1.084 (0.893–1.315) | |||
| A/A | 117 (27.8) | 101 (25.2) | 1.130 (0.813–1.572) | |||||||
| HWE -p | 0.62 | 0.96 | ||||||||
| rs5742629 | A/A | 128 (30.4) | 157 (39.1) | 1 | 0.031 | A | 478 (56.8) | 500 (62.3) | 1 | 0.021 |
| A/G | 222 (52.7) | 186 (46.4) | 1.501 (0.988–2.281) | G | 364 (43.2) | 302 (37.7) | 1.261 (1.035–1.536) | |||
| G/G | 71 (16.9) | 58 (14.5) | 1.026 (0.689–1.527) | |||||||
| HWE -p | 0.13 | 0.80 | ||||||||
| rs12423791 | G/G | 219 (52.0) | 241 (60.1) | 1 | 0.064 | G | 608 (72.2) | 618 (77.1) | 1 | 0.024 |
| G/C | 170 (40.4) | 136 (33.9) | 1.467 (0.838–2.569) | C | 234 (21.8) | 184 (22.9) | 1.293 (1.034–1.616) | |||
| C/C | 32 (7.6) | 24 (6.0) | 1.067 (0.600–1.896) | |||||||
| HWE -p | 0.90 | 0.41 | ||||||||
| rs35766 | G/G | 44 (10.5) | 37 (9.2) | 1 | 0.177 | G | 275 (32.7) | 231 (28.8) | 1 | 0.090 |
| G/A | 187 (44.4) | 157 (39.2) | 0.771 (0.577–1.029) | A | 567 (67.3) | 571 (71.2) | 0.834 (0.676–1.029) | |||
| A/A | 190 (45.1) | 207 (51.6) | 0.772 (0.478–1.247) | |||||||
| HWE -p | 0.84 | 0.36 | ||||||||
| rs1457601 | T/T | 217 (51.5) | 240 (59.9) | 1 | 0.053 | T | 614 (72.9) | 620 (77.3) | 1 | 0.040 |
| T/A | 180 (42.8) | 140 (34.9) | 0.889 (0.475–1.662) | A | 228 (27.1) | 182 (22.7) | 1.265 (1.011–1.583) | |||
| A/A | 24 (5.7) | 21 (5.2) | 1.264 (0.684–2.335) | |||||||
| HWE –p | 0.09 | 0.92 |