Figure 2. Subunit profile of lens proteins of WNIN/Ob and WNIN/GR-Ob rat. Representative subunit profile and protein cross-linking of the soluble fraction of lens of WNIN/Ob (top panel) and WNIN/GR-Ob rats (bottom panel) at different ages. Soluble lens protein was resolved on a 12% polyacrylamide gel under reducing conditions. Lane 1: molecular weight markers, lane 2: lean (3-months), lane 3: lean (6-months), lane 4: lean (12-months), lane 5: obese (3-months), lane 6: obese (6-months) and lane 7: obese (12-months).