Molecular Vision: Park, Mol Vis 2012; 18:488-494. Table 2

Table 2. Ocular findings in Korean patients with congenital aniridia.

Case No	Age/gender	Inheritance	BCVA (OD/OS)	Nystagmus	Keratopathy	Cataract	Glaucoma	Macular hypoplasia	Comments
1-1	27/F	Familial	0.1/0.1	+	Grade II	+	-	+
1-2	3Mon/F	Familial	F&F (+)	+	Grade IV	-	-	uncheckable	Corneal opacity
2	34/M	Sporadic	0.2/0.16	+	Grade I	+	-	-
3	15/M	Sporadic	0.25/0.16	+	-	+	-	-
4	1/F	Sporadic	F&F (+)	+	Grade II	+	-	+
5	24/M	Familial	0.04/0.04	+	Grade II	+	+, eyedrops	+
6-1	31/F	Sporadic	HM/0.02	+	Grade IV	+	+, eyedrops	+	Partial aniridia
6-2	1/M	Familial	F&F (+)	+	-	+	-	+
7-1	8/F	Familial	0.1/FC 30 cm	+	Grade III	+	-	+
7-2	40/M	Familial	FC 30 cm /0.1	+	Grade IV	+	+, eyedrops	+
8-1	48/F	Familial	0.02/0.02	+	Grade IV	+	-	+
8-2	15/F	Familial	0.16/0.06	+	Grade I	+	+, surgery	+	Valve implant
9	21/M	Sporadic	0.32/0.2	+	-	-	-	+
10	3/M	Sporadic	FC10 cm/LP-	+	Grade IV	+	+, eyedrops	uncheckable	Corneal opacity
11	30/M	Familial	0.1/FC 30 cm	+	Grade IV	+	-	+
12	15/F	Familial	FC50 cm/0.1	+	Grade I	+	-	+
13	8/M	Sporadic	0.16/0.2	+	Grade II	+	-	+
14	4/M	Familial	0.16/0.16	+	-	-	+, eyedrops	+
15	30/M	Familial	0.02/0.1	+	Grade III	+	+, eyedrops	+
16	48/F	Familial	0.04/0.04	+	Grade IV	+	-	+
17	16/M	Familial	0.06/0.06	+	Grade I	+	-	+	Partial aniridia
18	8Mon/M	Sporadic	F&F (+)	+	-	-	-	-

M: Male; F: Female; F&F: Fix and follow; PD: paired domain; LNK: linker domain; HD: Homeodomain; PST: proline-, serine-, and threonine-rich transregulatory domain. Keratopathy was graded as follows: grade 0, clear; grade 1, peripheral mudding with ingrowth of neovascular tissue not exceeding 1 mm from the limbal arch; grade II, peripheral neovascularization in at least the peripheral half of the cornea, corneal clouding, and subepithelial fibrosis; grade III, involvement of the central cornea.