Table 5 of
An, Mol Vis 2012; 18:471-478. Table 5 of
An, Mol Vis 2012; 18:471-478.
Table 5. Six tSNPs and their relationships to extreme myopia (refraction in case ≤-10 D; in control ≥-0.5D).
| SNP (major/minor) | status | Major homozygote | Heterozygote | Minor homozygote | MAF | p value |
|---|---|---|---|---|---|---|
| rs308442 | Case | 76 (66.1%) | 35 (30.4%) | 4 (3.5%) | 18.7% | 0.7511* |
| (T/A) | Control | 363 (62.7%) | 187 (32.3%) | 29 (5.0%) | 21.2% | |
| rs17473132 | Case | 118 (92.2%) | 10 (7.8%) | 0 (0.0%) | 3.9% | 0.4028* |
| (G/A) | Control | 520 (88.3%) | 68 (11.5%) | 1 (0.2%) | 5.9% | |
| rs308379 | Case | 35 (26.7%) | 77 (58.8%) | 19 (14.5%) | 43.9% | 0.0276 |
| (A/T) | Control | 209 (35.4%) | 271 (45.9%) | 111 (18.8%) | 41.7% | |
| rs308381 | Case | 123 (93.9%) | 8 (6.1%) | 0 (0.0%) | 3.1% | 0.8645 |
| (T/C) | Control | 560 (93.5%) | 39 (6.5%) | 0 (0.0%) | 3.3% | |
| rs1048201 | Case | 28 (21.4%) | 72 (55.0%) | 31 (23.7%) | 51.1% | 0.784 |
| (C/T) | Control | 144 (24.2%) | 314 (52.8%) | 137 (23.0%) | 49.4% | |
| rs3804158 | Case | 47 (36.2%) | 64 (49.2%) | 19 (14.6%) | 39.2% | 0.9697 |
| (G/A) | Control | 216 (36.4%) | 286 (48.2%) | 91 (15.4%) | 39.5% |