Table 4 of
An, Mol Vis 2012; 18:471-478. Table 4 of
An, Mol Vis 2012; 18:471-478.
Table 4. The association between tSNPs and their relationships to high myopia (refraction in case ≤-6 D; in control ≥-1.5D).
| SNP (major/minor) | Status | Major homozygote | Heterozygote | Minor homozygote | MAF | p value |
|---|---|---|---|---|---|---|
| rs308442 | Case | 642 (64.8%) | 317 (32.0%) | 31 (3.1%) | 19.1% | 0.2293 |
| (T/A) | Control | 620 (63.7%) | 308 (31.7%) | 45 (4.6%) | 20.5% | |
| rs17473132 | Case | 930 (88.6%) | 118 (11.2%) | 2 (0.2%) | 5.8% | 0.9119* |
| (G/A) | Control | 877 (88.5%) | 111 (11.2%) | 3 (0.3%) | 5.9% | |
| rs308379 | Case | 348 (33.2%) | 516 (49.1%) | 186 (17.7%) | 42.3% | 0.6037 |
| (A/T) | Control | 335 (33.8%) | 467 (47.1%) | 189 (19.1%) | 42.6% | |
| rs308381 | Case | 991 (92.3%) | 81 (7.6%) | 1 (0.1%) | 3.9% | 0.4931* |
| (T/C) | Control | 940 (93.3%) | 65 (6.5%) | 2 (0.2%) | 3.4% | |
| rs1048201 | Case | 260 (24.4%) | 532 (50.0%) | 272 (25.6%) | 50.6% | 0.2736 |
| (C/T) | Control | 245 (24.5%) | 529 (52.8%) | 227 (22.7%) | 49.1% | |
| rs3804158 | Case | 366 (34.8%) | 497 (47.3%) | 188 (17.9%) | 41.5% | 0.5546 |
| (G/A) | Control | 360 (36.1%) | 477 (47.8%) | 161 (16.1%) | 40.0% |