Molecular Vision: Chua, Mol Vis 2012; 18:431-438. Table 2

Table 2. Aqueous cytokine concentrations in glaucoma and non-glaucomatous cataract groups.

	Cataract (n=23)			Glaucoma (n=38)
Cytokines	Median	Range	Measurable	Median	Range	Measurable	p-value^a	Sensitivity
IL-2*	2.16	0–8	14/23	3.01	0–27	34/38	0.154	1.6
IFN-γ*	12.73	0–91	12/23	26.98	0–1167	36/38	0.002	6.4
IL-13	3.85	0–8	19/23	4.82	0–46	35/38	0.432	0.7
IL-17	2.27	0–11	8/23	3.98	0–241	22/38	0.227	3.3
IL-6*	2.23	0–14	9/23	4.02	0–89	27/38	0.789	2.6
IL-10*	1.45	0–5	18/23	1.91	0–64	37/38	0.050	0.3
IL-12*	7.15	0–27	17/23	14.06	0–68	36/38	0.003	3.5
IL-1β*	0.60	0–6	14/23	0.72	0–5	33/38	1.000	0.6
TNF-α*	9.58	0–34	16/23	12.65	0–82	35/38	0.086	6.0
IL-1Ra	8.58	3–96	10/17	8.74	0–84	14/34	1.000	5.5
IL-15	8.50	6–29	17/17	9.00	0–26	33/34	1.000	2.4
IFN-α*	26.24	0–139	16/22	37.90	0–311	37/38	0.034	4.3
CCL2	180.89	32–962	23/23	295.22	0–1072	37/38	0.086	1.1
CCL4	16.94	4–137	23/23	33.06	1–229	37/38	0.056	2.4
CCL5	6.30	0–25	16/17	6.30	0–39	33/34	1.000	1.8
CCL11	4.90	0–10	12/17	5.50	0–17	29/34	1.000	2.5
CXCL8	3.08	1–20	22/23	5.58	0–81	36/38	0.060	1.0
CXCL9*	62.20	0–3603	18/20	214.97	21–1351	38/38	0.006	1.2
CXCL10	56.27	0–5038	20/22	147.93	0–4677	37/38	0.290	6.1
IL-7*	1.09	0–15	10/23	1.92	0–4	31/38	0.728	1.1
IL-9*	5.50	0–11	15/17	7.57	0–17	33/34	0.032	2.5
GM-CSF*	135.45	0–766	18/23	164.05	0–6815	37/38	0.301	2.2
PDGF-BB	3.11	0–14	11/17	2.26	0–9	27/34	1.000	2.9
Basic-FGF	10.62	7–44	17/17	11.39	0–35	33/34	1.000	1.9
VEGF	43.73	22–124	17/17	54.35	0–151	33/34	1.000	3.1

The aqueous concentrations of IFN-γ, IL-10, IL-12, IFN-α, CXCL9 and IL-9 were significantly elevated in the glaucoma group compared to the cataract group (significant p-values are highlighted in bold). ^a p-values were obtained from Mann–Whitney U test with Bonferroni correction. *p<0.05 for the comparison of the percentage of measurable samples between glaucoma and cataract groups using Pearson’s χ² analysis. All concentrations of cytokines are in pg/ml.