Figure 4. TGFBI mutations in 3 families with corneal dystrophies. A: A heterozygous C→T transition (R555W) in exon 12 in the proband of the NTUH-6 family. B: A heterozygous C→T transition (R124C) in exon 4 in the proband of the NTUH-15 family. C: A heterozygous C→A transition (A546D) in exon 12 in the proband of the NTUH-11 family.