Table 1 of
Young, Mol Vis 2012; 18:3064-3069. Table 1 of
Young, Mol Vis 2012; 18:3064-3069.
Table 1. Summary of known clinical features of the affected family members
| Pedigree number | Age | Sex | Age at diagnosis | BCVA | Highest recorded IOP (mmHg) | Centralcorneal thickness (µm) | Visual field defect | Cup/Disc Ratio | IOP treatment | MYOC mutations | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OD | OS | OD | OS | OD | OS | OD | OS | OD | OS | ||||||
| V:3 | 35 | F | 34 | 6/6 | 6/6 | 37 | 36 | 569 | 566 | N | N | 0.4 | 0.3 | Latanoprost OU | Gln368STOP/Thr377Met |
| V:5 | 34 | F | - | 6/6 | 6/6 | 20 | 18 | 567 | 566 | N | N | 0.4 | 0.4 | - | Gln368STOP/Thr377Met |
| V:6 | 29 | M | 26 | 6/18 | 6/5 | 54 | 29 | 582 | 584 | Y | Y | 0.5 | 0.4 | 3 anti-glaucoma agents OS Trabeculectomy OD age 27 | Gln368STOP/Thr377Met |
| V:7 | 26 | M | - | 6/5 | 6/6 | 19 | 19 | 552 | 556 | N | N | 0.2 | 0.2 | - | Gln368STOP |
| V:8 | 26 | F | 25 | 6/5 | 6/5 | 41 | 37 | 547 | 547 | N | N | 0.4 | 0.7 | Bimatoprost OU | Gln368STOP/Thr377Met |
| IV:9 | 63 | F | - | 6/9 | 6/9 | 17 | 16 | 566 | 561 | N | N | 0.5 | 0.5 | - | Gln368STOP |