Table 2 of
Su, Mol Vis 2012; 18:3057-3063. Table 2 of
Su, Mol Vis 2012; 18:3057-3063.
Table 2. Summary of mutations responsible for Y-suture cataract.
| Gene | Sequence change | Lens phenotype | Ethnicity | Reference |
|---|---|---|---|---|
| FTL | 32 G>A | Y-suture congenital cataract | Indian | [6] |
| GJA8 | 235G>C | Full moon with Y-suture cataract | Indian | [7] |
| GJA8 | 262C>A | Y-suture cataract | Indian | [8] |
| MIP | c.319G>A | one eye exhibited Y-suture and nuclear pulverulent opacification of the lens, while the others exhibited complete opacification | Chinese | [10] |
| BFSP2 | 697–699delGAA | Y-suture cataract | Chinese | [5] |
| BFSP2 | 697–699delGAA* | Congenital nuclear and sutural cataract | American | [9] |
| BFSP2 | 696–698delGAA | Progressive sutural congenital cataract | Chinese | [11] |
| BFSP2 | 696–698delGAA | Progressive congenital cataract with suture and cortex opacity | Chinese | [12] |
| CRYBA1 | IVS3+1G>A | Sutural, nuclear, and peripheral cortical opacity | Australia | [13] |
| CRYBA1 | IVS3+1G>C | Zonular and sutural cataract | Brazilian | [14] |
| CRYBA1 | IVS3+1G>C | Y-shaped sutural cataract | Saudi Arabian | [15] |
| CRYBA1 | IVS3+1 G>A | Progressive childhood cataract with Y-suture opacity | Chinese | [16] |
| CRYBA1 | IVS3+1 G>T | Y-suture opacity | Chinese | [17] |
| CRYBB2 | 475C>T, 483C>T | Sutural cataract and cerulean opacities | Indian | [18] |
| CRYBB1 | 658G>T | Dustlike cataract with the anterior and posterior Y-suture opacities | American | [19] |