Table 2 of Perkins, Mol Vis 2012; 18:3029-3048.

Table 2. Bcl-xl-mediated protection of lead-induced substructural alterations in rod spherule and cone pedicle mitochondria.

Mitochondrial substructural
measure Rod spherule  Cone pedicle
Lead Bcl-xL/Lead Lead Bcl-xL/Lead
Cristae surface/Mito surface ↓↓ ↓ ↑↑ ±
Cristae volume/Mito volume ↓↓ ± ↑↑ ±
# Crista segments/Volume ± ± ↑↑↑ ↑↑↑
# Cristae/Volume ± ± ± ±
# Segments/Crista ↑ ± ↑↑ ↑↑
Fraction of cristae with multiple segments ↑↑↑ ± ↑↑↑ ↑↑↑
Crista junction diameter ± ± ± ±
Crista junction density ± ± ± ±

Arrows indicate relative significant percent change from controls as follows: 1 arrow=≤±35%; 2 arrows=±36%–89%; 3 arrows=≥±90%. The symbol ±=not significantly different from controls.

Perkins, Mol Vis 2012; 18:3029-3048. http://www.molvis.org/molvis/v18/a310

©2012 Molecular Vision http://www.molvis.org/molvis/

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