Figure 6. Chemotactic response in response to CC-chemokine ligand 2 (CCL2) increases twofold in CCR2-overexpressing microglia. The number of transmigrated cells in each condition represents the chemotactic response of the microglia. The number of migrating microglia overexpressing CCR2 (CCR2-MG) is approximately twofold compared to untreated microglia (MG; A) and GFP-transduced microglia (GFP-MG; B) at the same CCL2 concentration and posttreatment time points.