Table 1 of
Janin-Manificat, Mol Vis 2012; 18:2896-2908. Table 1 of
Janin-Manificat, Mol Vis 2012; 18:2896-2908.
Table 1. Summary of the main findings presented in this study.
| Air/liquid conditions | Epithelium/limbus preserved, unwounded | Epithelium/limbus preserved, wounded | Epithelium/limbus preserved, wounded, TGF-β1 | Epithelium/limbus removed, wounded, TGF- β1 |
|---|---|---|---|---|
| Keratocyte activation, stromal disorganization | - | + | ++ | ++ |
| Myofibroblast differentiation (α-SMA) | - | - | + | + |
| ECM production (fibronectin, tenascin C, thrombospondin-1) | - | + | ++ | ++ |
| Corneal opacity | - | - | - | + |
| Immersed conditions | Epithelium/limbus preserved, unwounded | Epithelium/limbus preserved, wounded | Epithelium/limbus preserved, wounded, TGF- β1 | Epithelium/limbus removed, wounded, TGF- β1 |
|---|---|---|---|---|
| Keratocyte activation, stromal disorganization | - | - | + | + |
| Myofibroblast differentiation (α-SMA) | - | - | + | + |
| ECM production (fibronectin, tenascin C, thrombospondin-1) | - | + | ++ | ++ |
| Corneal opacity | - | - | - | + |