Figure 2. Bodyweight, blood glucose and insulin levels. Wild-type and σR1 KO mice were made diabetic using streptozotocin (STZ) at 3 weeks and the bodyweights and insulin levels determined from blood samples harvested at euthanasia. A: Bodyweights are provided for mice before STZ injection; B: Bodyweights are provided for mice at the termination of the experiment (12 weeks following STZ injection); C: Blood glucose levels are provided for mice 12 weeks following STZ injection; and D: Insulin levels are provided for mice 12 weeks following STZ injection. For these studies, 10 mice were tested per group (n=10). The data were significant as shown by the asterisk representing statistical analysis. (The asterisks denote between which groups there are significant statistical differences: *, p<0.05; **, p<0.01; ***, p<0.001).