Table 3 of
Honda, Mol Vis 2012; 18:2796-2804. Table 3 of
Honda, Mol Vis 2012; 18:2796-2804.
Table 3. Summary of the genotype association analysis for selective SNPs associated with the response to PDT.
| Genotype frequency (number of subjects) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| SNP ID | Major/Minor | Responder (n=73) | Non-responder (n=64) | Dominant model | Recessive model | ||||||
| allele | Major homo | Hetero | Minor homo | Major homo | Hetero | Minor homo | OR (95%CI) | P value (corrected P) | OR (95%CI) | P value (corrected P) | |
| rs3211851 | A/C | 0.53 (39) | 0.37 (27) | 0.1 (7) | 0.31 (20) | 0.55 (35) | 0.14 (9) | 0.40 (0.20–0.80) | 0.0085 (0.16) | 0.65 (0.23–1.85) | 0.42 (1.0) |
| rs3173798 | T/C | 0.4 (29) | 0.4 (29) | 0.2 (15) | 0.14 (9) | 0.61 (39) | 0.25 (16) | 0.25 (0.11–0.58) | 6.0×10–4 (0.011) | 0.78 (0.35–1.73) | 0.53 (1.0) |
| rs3211908 | C/T | 0.73 (53) | 0.26 (19) | 0.01 (1) | 0.59 (38) | 0.33 (21) | 0.08 (5) | 0.55 (0.27–1.13) | 0.1 (1.0) | 0.16 (0.02–1.44) | 0.057 (1.0) |