Table 2 of
Honda, Mol Vis 2012; 18:2796-2804. Table 2 of
Honda, Mol Vis 2012; 18:2796-2804.
Table 2. Summary of the allelic association analysis regarding the response to PDT.
| SNP ID | Location | Major/Minor allele | Minor allelic frequency (No. of genotypes: major homo/hetero/minor homo) | Association analysis results | ||
|---|---|---|---|---|---|---|
| Responder (n=73) | Non-responder (n=64) | Allele OR (95% CI) | P value | |||
| rs12531609 | Intron 1 | A/T | 0.12 (56/16/1) | 0.14 (48/14/2) | 0.86 (0.43–1.72) | 0.68 |
| rs3211816 | Intron 3 | G/A | 0.38 (28/35/10) | 0.34 (27/30/7) | 1.16 (0.70–1.92) | 0.57 |
| rs10499862 | Intron 3 | T/C | 0.12 (56/16/1) | 0.14 (48/14/2) | 0.86 (0.43–1.72) | 0.68 |
| rs3211849 | Intron 3 | G/A | 0.34 (35/26/12) | 0.24 (36/25/3) | 1.56 (0.94–2.61) | 0.082 |
| rs3211851 | Intron 3 | A/C | 0.28 (39/27/7) | 0.41 (20/35/9) | 0.54 (0.32–0.92) | 0.02 |
| rs1054516 | Intron 3 | T/C | 0.47 (22/33/18) | 0.38 (25/29/10) | 1.41 (0.88–2.26) | 0.15 |
| rs3173798 | Intron 3 | T/C | 0.4 (29/29/15) | 0.55 (9/39/16) | 0.54 (0.33–0.88) | 0.012 |
| rs3211870 | Intron 4 | C/T | 0.44 (21/40/12) | 0.48 (16/34/14) | 0.82 (0.49–1.35) | 0.42 |
| rs1358337 | Intron 4 | A/G | 0.43 (24/35/14) | 0.38 (23/34/7) | 1.28 (0.78–2.11) | 0.33 |
| rs3211883 | Intron 4 | T/A | 0.32 (37/26/10) | 0.43 (19/35/10) | 0.62 (0.38–1.01) | 0.054 |
| rs3173800 | Intron 4 | A/T | 0.25 (41/27/5) | 0.2 (40/23/1) | 1.42 (0.79–2.57) | 0.24 |
| rs1924 | Intron 5 | G/A | 0.22 (46/22/5) | 0.3 (31/28/5) | 0.67 (0.39–1.16) | 0.15 |
| rs17154232 | Intron 6 | G/C | 0.12 (57/15/1) | 0.12 (49/14/1) | 0.92 (0.45–1.91) | 0.83 |
| rs17154233 | Intron 6 | A/C | 0.16 (52/19/2) | 0.11 (51/12/1) | 1.51 (0.74–3.05) | 0.25 |
| rs3211908 | Intron 7 | C/T | 0.14 (53/19/1) | 0.24 (38/21/5) | 0.54 (0.29–0.99) | 0.042 |
| rs17154258 | Intron 8 | A/G | 0.15 (53/18/2) | 0.2 (41/20/3) | 0.70 (0.38–1.31) | 0.26 |
| rs1527483 | Intron 11 | G/A | 0.2 (48/21/4) | 0.3 (32/26/6) | 0.60 (0.35–1.04) | 0.068 |
| rs3211958 | Intron 14 | A/G | 0.37 (29/34/10) | 0.42 (21/32/11) | 0.80 (0.49–1.31) | 0.38 |
| rs7755 | 3′UTR | A/G | 0.48 (22/32/19) | 0.38 (21/38/5) | 1.57 (0.95–2.60) | 0.074 |