Table 3 of Miyake, Mol Vis 2012; 18:2726-2735.

Table 3. Genotype counts, associations, and odds ratios in patients with high myopia, extreme myopia and pooled control participants.

SNP Genotype Pooled control High myopia Extreme myopia
n Genotype frequency
p value*		 Allele
frequency p value*		 HWE P value n Nominal p value† Adjusted p value‡ Adjusted odds
ratio (95%
confidence interval)		 n Nominal p value† Adjusted p value‡ Adjusted
odds ratio
(95% confidence interval)
rs2071754 CC 322 0.53 0.99 0.74 326 0.44 0.343 1.06 196 0.327 0.317 1.07
(C/T) CT 622


632

(0.94–1.18) 397

(0.94–1.21)

TT 312


344


215


rs644242 CC 968 0.95 0.95 0.15 1052 0.0105 0.00445 0.78 651 0.0294 0.0165 0.78
(C/A) CA 263


237

(0.65–0.92) 149

(0.64–0.95)

AA 25


14


8


rs3026354 AA 518 0.28 0.22 1 544 0.99 0.834 0.99 346 0.656 0.585 0.96
(A/G) AG 576


590

(0.88–1.11) 359

(0.84–1.10)

GG 160


171


104



* The difference in genotype and allele frequency between control 1 and control 2 were analyzed using a chi-square test. † Differences in the observed genotypic distribution were examined by chi-square test for trend. ‡ Age and sex adjustment were performed based on a logistic regression model. SNP: Single-nucleotide polymorphism, HWE: Hardy–Weinberg equilibrium

Miyake, Mol Vis 2012; 18:2726-2735. http://www.molvis.org/molvis/v18/a280

©2012 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535