Figure 3. Model of wild-type human mitochondrial ATP synthase subunit a (F-ATPase protein 6) (ATP6) (green) superimposed on a model of M181T mutant (cyan). The side chain conformation of Met181, Ser176, and Ile95 (green) in the wild-type and Thr181, Ser176, and Ile95 (cyan) in the mutant are represented with the balls and sticks. The conformation of Thr181, Ser176, and Ile95 side chains were different in the native and mutant protein.