Table 5 of
Jiao, Mol Vis 2012; 18:2633-2646. Table 5 of
Jiao, Mol Vis 2012; 18:2633-2646.
Table 5. Summary of association of myopia with markers on chromosome 15q14 and 15q25 from the literature and the present study.
| Locus | best SNPs* | Gene(s) | Study | Population | best P | best OR |
|---|---|---|---|---|---|---|
| 15q14 | rs634990 rs524952 |
GOLGA8B ACTC1 GJD2 | Solouki et al. [57] | European | 2.21×10−14 | 1.81 (1.42–2.36)# |
| rs634990 rs524952 |
Hayashi et al. [36] | Japanese | 8.781×10−7 | 1.32 (1.11–1.56) | ||
| rs634990 | Verhoeven et al. [37]** | European Japanese Singapore | 9.2×10−23^ | 1.88 (1.64–2.16)# | ||
| rs634990 | European | 3.87×10−12^ | na | |||
| rs8032019 | Asian | 9.65×10−4^ | na | |||
| rs634990 | present study | Han Chinese | 1.66×10−6+ | 1.75 (1.39–2.20) | ||
| 15q25 | rs8027411 rs939658 |
RASGRF1 | Hysi et al. [31] | European | 2.07×10−9 | 1.16 (1.02–1.28)# |
| rs8027411 rs939658 |
Hayashi et al. [36] | Japanese | 0.031 | 1.17 (1.03–1.33) | ||
| rs939661 | Verhoeven et al. [37]** | European Japanese Singapore | 1.22×10−4& | na | ||
| rs8027411 | present study | Han Chinese | 0.17+ | 0.9 (0.72–1.14) |