Table 3 of Jiao, Mol Vis 2012; 18:2633-2646.
Guangzhou | ||||||
---|---|---|---|---|---|---|
Region | SNP | Test | Myopia (300 total) | Control (308 total) | Odds ratio* | P** |
15q14 | rs634990 | AA | 73 | 125 | 1 | 1.91×10−5 |
GA | 156 | 144 | 1.86 (1.29–2.68) | 0.2 | ||
GG | 71 | 39 | 3.12 (1.92–5.07) | 4.25×10−4 | ||
G allele % | 0.5 | 0.36 | 1.75 (1.39–2.20) | 1.57×1−6 | ||
Additive | 1.45×10−6 | |||||
rs634990 | AA | 69 | 125 | 1 | 3.31×10−6 | |
TA | 161 | 143 | 2.04 (1.41–2.95) | 0.07 | ||
TT | 70 | 40 | 3.17 (1.95–5.16) | 9.22×10−4 | ||
T allele % | 0.5 | 0.36 | 1.78 (1.41–2.23) | 8.8×10−7 | ||
Additive | 7.01×10−7 | |||||
15q25 | rs8027411 | TT | 113 | 108 | 1 | 0.5 |
GT | 146 | 151 | 0.92 (0.65–1.31) | 0.92 | ||
GG | 41 | 49 | 0.80 (0.49–1.31) | 0.44 | ||
G allele % | 0.38 | 0.4 | 0.90 (0.72–1.14) | 0.39 | ||
Additive | 0.38 | |||||
rs17175798 | CC | 112 | 107 | 1 | 0.51 | |
TC | 148 | 152 | 0.93 (0.66–1.32) | 0.99 | ||
TT | 40 | 49 | 0.78 (9.48–1.28) | 0.37 | ||
T allele % | 0.38 | 0.4 | 0.90 (0.71–1.30) | 0.36 | ||
Additive | 0.35 | |||||
rs939658 | CC | 121 | 116 | 1 | 0.5 | |
TC | 139 | 147 | 0.93 (0.66–1.32) | 0.73 | ||
TT | 40 | 45 | 0.91 (0.69–1.30) | 0.65 | ||
T allele % | 0.37 | 0.39 | 0.92 (0.73–1.16) | 0.36 | ||
Additive | 0.48 | |||||
Chaoshan | ||||||
Region | SNP | Genotype | Myopia (96 total) | Control (96 total) | Odds Ratio | P** |
15q14 | rs634990 | AA | 28 | 34 | 1 | 0.35 |
GA | 48 | 46 | 1.26 (0.67–2.41) | 0.77 | ||
GG | 20 | 16 | 1.51 (0.66–3.47) | 0.46 | ||
G allele % | 0.46 | 0.41 | 1.23 (0.83–1.85) | 0.3 | ||
Additive | 0.3 | |||||
rs524952 | AA | 28 | 34 | 1 | 0.35 | |
TA | 48 | 46 | 1.26 (0.67–2.41) | 0.77 | ||
TT | 20 | 16 | 1.52 (0.66–3.47) | 0.46 | ||
T allele % | 0.46 | 0.41 | 1.24 (0.83–1.35) | 0.3 | ||
Additive | 0.3 | |||||
15q25 | rs8027411 | TT | 37 | 26 | 1 | 0.09 |
GT | 44 | 54 | 0.57 (0.30–1.08) | 0.15 | ||
GG | 14 | 15 | 0.66 (0.27–1.59) | 0.84 | ||
G allele % | 0.38 | 0.44 | 0.79 (0.52–1.19) | 0.21 | ||
Additive | 0.2 | |||||
rs17175798 | CC | 37 | 27 | 1 | 0.13 | |
TC | 44 | 53 | 0.61 (0.32–1.15) | 0.19 | ||
TT | 14 | 15 | 0.68 (0.28–1.64) | 0.84 | ||
T allele % | 0.41 | 0.38 | 0.79 (0.52–1.18) | 0.25 | ||
Additive | 0.24 | |||||
rs939658 | CC | 35 | 31 | 1 | 0.68 | |
TC | 48 | 50 | 0.93 (0.66–1.32) | 0.77 | ||
TT | 13 | 15 | 0.91 (0.69–1.30) | 0.54 | ||
T allele % | 0.37 | 0.39 | 0.92 (0.73–1.16) | 0.53 | ||
Additive | 0.52 | |||||
Combined | ||||||
Region | SNP | Genotype | Myopia (396 total) | Control (404 total) | Odds Ratio* | P** |
15q14 | rs634990 | AA | 97 | 159 | 1 | 6.63×10−6 |
GA | 209 | 189 | 1.81 (1.32–2.50) | 0.09 | ||
GG | 90 | 56 | 2.63 (1.73–4.00) | 0.001 | ||
G allele % | 0.49 | 0.37 | 1.75 (1.39–2.20) | 1.66×10−6 | ||
Additive | 1.42×10−6 | |||||
rs524952 | AA | 101 | 159 | 1 | 2.89×10−5 | |
TA | 204 | 190 | 1.69 (1.23–2.32) | 0.2 | ||
TT | 91 | 55 | 2.60 (1.72–3.95) | 6.10×10−4 | ||
T allele % | 0.49 | 0.37 | 1.78 (1.41–2.23) | 2.72×10−6 | ||
Additive | 2.59×10−6 | |||||
15q25 | rs8027411 | TT | 150 | 134 | 1 | 0.16 |
GT | 190 | 205 | 0.83 (0.61–1.12) | 0.43 | ||
GG | 55 | 64 | 0.77 (0.50–1.18) | 0.44 | ||
G allele % | 0.38 | 0.41 | 0.90 (0.72–1.14) | 0.17 | ||
Additive | 0.17 | |||||
rs17175798 | CC | 149 | 134 | 1 | 0.38 | |
TC | 192 | 205 | 0.84 (0.62–1.14) | 0.52 | ||
TT | 54 | 64 | 0.75 (0.49–1.17) | 0.19 | ||
T allale % | 0.38 | 0.41 | 0.90 (0.71–1.13) | 0.17 | ||
Additive | 0.16 | |||||
rs939658 | CC | 156 | 147 | 1 | 0.55 | |
TC | 187 | 197 | 0.93 (0.66–1.32) | 0.66 | ||
TT | 53 | 60 | 0.83 (0.54–1.28) | 0.38 | ||
T allele % | 0.37 | 0.39 | 0.91 (0.74–1.11) | 0.37 | ||
Additive | 0.35 |