Figure 5. Partial sequence analysis of membrane frizzled-related protein gene (MFRP) gene exon 5 in the MFRP-related ophthalmological syndrome. Normal sequence from the control DNA is shown in the top panel.
A homozygous C: deletion at nucleotide position 492, named c.492delC (codon 164) in DNA from the affected individual is shown in the bottom
sequence. The deleted nucleotide is highlighted with an arrow in the normal DNA. This mutation predicts a truncated MFRP protein