Figure 4. Normal rat eye and rat eyes at the different stages of experimental autoimmune uveitis. The MRI images of the normal: A and that of the eyes affected by experimental autoimmune uveitis (EAU): B-F were acquired in vivo at 4.7 T. The inflamed ciliary body and a small retinal detachment were the first signs of the disease detected in vivo by magnetic resonance imaging (MRI) and confirmed ex vivo by histology. Detection of the inflamed ciliary body using MRI is shown with a white arrow in B Inflammation of the ciliary body was confirmed by histology. The smallest retinal detachment detected in vivo using MRI is shown with a white arrow in C and confirmed on the corresponding histological section ex vivo. The maximum retinal detachment was detected at the peak and post peak of EAU in vivo using MRI, E and confirmed ex vivo by histology. The spatial resolution of each MRI image is 60×60×700 μm³, and the acquisition time was 30 min. All MRI images in this picture are T₂-weighted. The images were reproduced from [38] with permission from John Wiley & Sons Ltd.