Figure 3. Images of patient 2. Fundus autofluorescence (FAF) images C and D correspond with the white square regions in images A and B, respectively. The horizontal white dashed lines represent the position of the spectral domain-optical coherence tomography (SD-OCT) images E and F on the corresponding en face image. FAF revealed widespread retinal disease. Relative foveal sparing was present bilaterally as evidenced by a uniform autofluorescence pattern at the foveae (black arrows). The corresponding SD-OCT images revealed relative preservation of the inner segment–outer segment junctions of the photoreceptors (IS/OS), external limiting membrane (ELM), and outer nuclear layer (ONL) in this region. The horizontal borders of the regions with preserved IS/OS are indicated by the vertical white dashed lines on the corresponding FAF and SD-OCT images. Outside these regions, absence of IS/OS was associated with functionally preserved retinal pigment epithelium (RPE), at least as identified by FAF (C, D). Qualitatively normal thickness RPE was also observed in regions with loss of IS/OS (F, white arrow).Corresponding size bars for A and B, C and D, and E and F are included in A, C and E, respectively