Figure 7. mRNA expression of UM cell lines after bevacizumab treatment mRNA expression was measured with qPCR after exposure to different doses of bevacizumab under hypoxic conditions for 24 h. Expression is shown in normalized fold. Treatment with bevacizumab induced VEGF-A and GLUT-1 mRNA. AVA1=equivalent human dose: 1.25 mg/ 5.46 ml; AVA10=10 times the equivalent human dose: 12.5 mg/5.46 ml; AVA20=20 times the equivalent human dose: 25 mg/ 5.46 ml; CO=control group: culture medium.