Figure 3. Proliferation of B16F10 cells after bevacizumab treatment. Bevacizumab was added to B16F10 cells in vitro under normoxic (top) and hypoxic (bottom) circumstances and proliferation was measured by WST-1 assay on days one, two and three after addition of bevacizumab. Cell density is expressed in absorbance (optical density, OD). A high dose of bevacizumab inhibited cell growth under hypoxic conditions.