Table 5 of
Venkatesan, Mol Vis 2012; 18:2420-2437. Table 5 of
Venkatesan, Mol Vis 2012; 18:2420-2437.
Table 5. Down -Regulated Genes in post HMGA2 silenced in Y79 cells (cDNA microarray analysis).
| Gene classification | Gene Description (Homo sapiens, gene, mRNA) | Gene symbol | Fold change | GeneBank accession | Chromosome location |
|---|---|---|---|---|---|
| Angiogenesis | Fscin homolog 1, actin-bundling protein (S .rpuratus) | FSCN1 | −1.43 | NM_003088 | 17p13.3 |
| Apoptosis | cDNA FLJ13706 fis, clone PLACE2000317 | STAMBP | −2.611 | NM_201647 | 18q23 |
| RRP5 protein homolog (Programmed cell death protein 11) | PDCD11 | −1.24 | NM_198490 | 3q21.3 | |
| Anti-apoptosis | G-2 and S-phase expressed 1 | GTSE1 | −1.089 | NM_016426 | Xp11.23 |
| High-mobility group box 1 | HMGB1 | −1.047 | NM_002128 | 20q13.32 | |
| Cell cycle & differentiation | Cyclin-dependent kinase 6, mRNA | CDK6 | −1.55 | NM_001259 | 14q11.2 |
| CNDP dipeptidase 2 (metallopeptidase M20 family) | CNDP2 | −1.084 | NM_018235 | 9q33.3 | |
| Epithelial mesenchymal transition | Snail homolog 1 (Drosophila) | SNAI1 | −1.155 | NM_005985 | 11q13.1 |
| Transcription factor 4 | TCF4 | −1.313 | NM_003199 | 8q24.21 | |
| Cell proliferation | Cyclin-dependent kinase 6 | CDK6 | −1.55 | NM_001259 | 12q13.3 |
| Fibroblast growth factor receptor-like 1 | FGFRL1 | −1.822 | NM_01004356 | 10q26.13 | |
| c-src tyrosine kinase | CSK | −1.14 | NM_004383 | 14q11.2 | |
| Antigen identified by monoclonal antibody Ki-67 | MKI67 | −2.378 | NM_002417 | 17q21.32 | |
| Cell division cycle 25 homolog B (S. pombe) | CDC25B | −1.319 | NM_021873 | 1p34.1 | |
| E2F transcription factor 4, p107/p130-binding | E2F4 | −1.354 | NM_001950 | 8p21.1 | |
| Tumor protein p53 inducible protein 11 | TP53I11 | −1.143 | NM_006034 | 2p13.1 | |
| Oncogene | v-abl Abelson murine leukemia viral oncogene homolog 1 | ABL1 | −1.167 | NM_005157 | 22q13.2 |
| RAB22A, member RAS oncogene family | RAB22A | −1.554 | NM_020673 | 6p21.33 | |
| v-myc myelocytomatosis viral oncogene homolog (avian) | MYC | −1.526 | NM_002467 | 12p13.33 | |
| v-crk sarcoma virus CT10oncogene homolog (avian) transcript 2 | CRK | −1.775 | NM_016823 | 1p35.1 | |
| v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | MYBL2 | −1.231 | NM_002466 | 21q22.11 | |
| ELK1, member of ETS oncogene family | ELK1 | −1.673 | NM_005229 | 10q24.33 | |
| Tumor suppressors | Breakpoint cluster region, transcript variant 1 | BCR | −1.428 | NM_004327 | 22q13.31 |
| Tumor protein p53 inducible nuclear protein 2 | TP53INP2 | −1.301 | NM_021202 | 11q14.1 | |
| Transcription factors | Multiple endocrine neoplasia, transcript variant e1E | MEN1 | −1.526 | NM_130803 | 12q13.13 |
| ELK1, member of ETS oncogene family | ELK1 | −1.673 | NM_005229 | 7q34 |