Table 4 of
Venkatesan, Mol Vis 2012; 18:2420-2437. Table 4 of
Venkatesan, Mol Vis 2012; 18:2420-2437.
Table 4. Up - Regulated Genes in post HMGA2 silenced in Y79 cells (cDNA microarray analysis).
| Gene classification | Gene Description (Homo sapiens, gene, mRNA) | Gene symbol | Fold change | Gene Bank Accession | Chromosome location |
|---|---|---|---|---|---|
| Angiogenesis | Lectin, galactoside-binding, soluble, 3 binding protein | GALS3BP | 1.1 | NM_005567 | 17q25.3 |
| Angiogenic factor with G patch and FHA domains 1 | AGGF1 | 1.093 | NM_018046 | 5q13.3 | |
| Cell cycle, differentiation | Transforming growth factor, beta 3 | TGFB3 | 1.511 | NM_003239 | 14q24.3 |
| Activating transcription factor 3, transcript variant 2 | ATF3 | 2.448 | NM_004024 | 1q32.3 | |
| Cell proliferation and invasion | Matrix metallopeptidase 10 (stromelysin 2) | MMP10 | 2.958 | NM_002425 | 11q22.2 |
| p53 binding protein (mouse), transcript variant | MDM2 | 1.764 | NM_002392 | 12q15 | |
| v-fos FBJ murine osteosarcoma viral oncogene homolog | FOS | 2.76 | NM_005252 | 14q24.3 | |
| MMP 2 (72 kDa gelatinase A, 72 kDa type IV collagenase) | MMP2 | 1.338 | NM_004530 | 16q12.2 | |
| Anti – proliferation | Maternally expressed 3 | MEG3 | 1.53 | NR_002766 | 14q32.2 |
| Apoptosis | Apoptosis-related cysteine peptidase, transcript variant C | CASP8 | 1.22 | NM_033356 | 2q33.1 |
| BCL2-interacting killer (apoptosis-inducing) | BIK | 1.319 | NM_001197 | 22q13.2 | |
| Damage-regulated autophagy modulator | DRAM | 1.965 | NM_018370 | 12q23.2 | |
| Cyclin-dependent kinase inhibitor1A, transcriptvariant2 | CDKN1A | 2.937 | NM_078467 | 6p21.31 | |
| Lectin, galactoside-binding, soluble, 7 (galectin 7) | LGALS7 | 3.384 | NM_002307 | 19q13.2 | |
| Nuclear protein 1, transcript variant 2 | NUPR1 | 2.818 | NM_012385 | 16p11.2 | |
| Insulin-like growth factor binding protein, transcript variant 1 | IGFBP1 | 1.575 | NM_000596 | 7p13 | |
| Epithelial mesenchymal | Keratin 19 | KRT19 | 3.498 | NM_002276 | 17q21.2 |
| Transition | Caveolin 2, transcript variant 1 | CAV2 | 1.57 | NM_001233 | 7q31.2 |
| Cadherin 1, type 1, E-cadherin (epithelial) | CDH1 | 1.57 | NM_004360 | 16q22.1 | |
| Tumor suppressors | Ras association (RalGDS/AF-6)domain family member10 | RASSF10S100A4 | 1.522 | NM_1080521 | 11p15.2 |
| S100 calcium binding protein A4, transcript variant 1 | RB1 | 3.891 | NM_002961 | 1q21.3 | |
| Retinoblastoma 1 | 1.099 | NM_000321 | 13q14.2 | ||
| Oncogenes | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | ETS1 | 1.583 | NM_005238 | 11q24.3 |
| Jun oncogene | JUN | 1.904 | NM_002228 | 1p32.1 |