Table 1 of
Venkatesan, Mol Vis 2012; 18:2420-2437. Table 1 of
Venkatesan, Mol Vis 2012; 18:2420-2437.
Table 1. Clinicopathological features of the primary RB tumors following the International Intraocular Retinoblastoma Classification (IIRC) with gene expression (by qRT–PCR).
| S/N | Age/Sex | Clinico pathological features | Log 2 ratio fold change | ||||||
|---|---|---|---|---|---|---|---|---|---|
| ELK1 | GTSE1 | CDK6 | E2F4 | DRAM | CDH1 | SNAI1 | |||
| 1 | 4/M | OS:PD tumor seen in iris surface, trabecular meshwork, diffuse CI with measuring >3 mm thickness, prelaminar, laminar invasion, invasion of anterior & middle portion of sclera . | ++ | - | ++ | ++ | - | NS | + |
| 2 | 3/F | OS: WD with formation of fleurettes, prelaminar invasion of ON. | ++ | ++ | ++ | ++ | + | NS | ++ |
| 3 | 2/M | OS:WD massive CI >3 mm, tumor cells invading the anterior, middle and posterior border of sclera with spill over into the orbital tissue. | ++ | ++ | ++ | ++ | + | + | NS |
| 4 | 4/M | OD:PD, there is full thickness diffuse CI measuring >3 mm, tumor cells touching the anterior border of scelra, prelaminar invasion of ON | ++ | ++ | ++ | ++ | + | NS | ++ |
| 5 | 8/ F | OD:UD, tumor cells adherent to iris surface, invasion of ciliary process, diffuse full thickness CI >3 mm, invasion of prelaminar, laminar & post laminar portion of ON,outer margin of sclera. | ++ | ++ | ++ | ++ | + | NS | ++ |
| 6 | 6mon/F | OS;MD, CI measuring >3mm, prelaminar invasion and laminar invasion of the ON. | ++ | ++ | ++ | ++ | + | + | ++ |
| 7 | 3/M | OS:PD, focal CI measuring <3 mm. | ++ | ++ | ++ | ++ | + | NS | ++ |
| 8 | 5/M | OD:UD prelaminar invasion of ON | ++ | - | ++ | ++ | + | NS | ++ |
| 9 | 2/F | OD: PD, tumor cells in iris surface, full thickness CI measuring 10 mmx7 mm.Sclera invasion. | ++ | ++ | ++ | ++ | + | NS | ++ |
| 10 | 1/F | OS: WD, focal choroid invasion measuring <3mm. | ++ | ++ | ++ | ++ | + | NS | ++ |