Figure 4. Fundus photographs (A, C: E, G: and spectral domain optical coherence tomography images B: D, F: H-J: in retinitis pigmentosa patients with missense mutations. In fundus images, areas of atrophy along the arcades (A; red arrowheads) and marked pigmentary changes E: were noted. In optical coherence tomography (OCT) images, intraretinal cyst or cystoid macular edema (CME; B: I; red arrow), severe foveal atrophy D: H, J: and normal range of foveal thickness F: were observed.