Table 5 of Mykkänen, Mol Vis 2012; 18:2338-2351.


Table 5. Gene set enrichment analyses (GSEA) of retinal expression in C57BL mice fed normal control diet (NCD), high fat diet (HFD) or bilberries (BB) in these diets for 12 weeks.

Limit1 Term Count Fold enrichment p-value2
HFD versus NCD
upregulated (n=431, 2 unknown)
   Dilated cardiomyopathy 7 3.5 0.01
   Hypertrophic cardiomyopathy (HCM) 6 3.3 0.03
   MAPK signaling pathway 11 1.9 0.06
down regulated (n=374, 3 unkwown)
   Apoptosis 11 6.2 0
   Calcium signaling pathway 10 2.6 0.02
   Melanogenesis 6 2.9 0.05
   Long-term potentiation 5 3.5 0.05
HFD+BB versus NCD
upregulated (n=395, 2 unknown)
   Systemic lupus erythematosus 7 3.5 0.01
   Colorectal cancer 6 3.6 0.02
down regulated (n=410, 3 unknown)
   Apoptosis 10 5 0
   Calcium signaling pathway 10 2.3 0.03
   Gap junction 6 3.2 0.05
HFD+BB versus HFD:
upregulated (n=393, 1 unknown)
   Systemic lupus erythematosus 7 3.4 0.02
down regulated (n=412, 4 unknown)
   Apoptosis 9 4.7 0
NCD+BB versus NCD:
upregulated (n=416, 2 unknown)
   Systemic lupus erythematosus 8 3.6 0.01
down regulated (n=389, 3 unknown)
   Apoptosis 9 5.1 0
   MAPK signaling pathwway 11 2 0.04
   Calcium signaling pathway 9 2.3 0.04