Figure 3. Typical angiography of retinal whole mounts is shown for different Royal College of Surgeons (RCS) rat treatment groups. A: Fluorescent micrographs represent RTL220, RTL101, IRBP1177–1191 peptide and vehicle-treated rats. The fluorescent pictures were taken from middle retinas around optic disc regions in A (RTL220 and RTL101), showing protective effects of RTL220 on the vasculature compared to the control rats presenting vascular leakage and abnormal vessels (arrows). B: Bar graph show the reduction in total counts of leaking vessels in RTL220-treated rats compared to the vehicle-treated rats (n=6, p=0.0018). C: Scheme of retinal flat mounts shows the area from which the leaking vessels were counted (box).