Table 2 of
Awadalla, Mol Vis 2012; 18:2247-2254.
Table 2. Allelic association results for the candidate genes in both Australian and Nepalese cohorts. P-values of less than 0.05 are highlighted in bold.
| Australian | Nepalese | |||||||
|---|---|---|---|---|---|---|---|---|
| Gene | SNP | Risk allele | p-value | OR (95% CI) | adjusted p-value* | p-value | OR (95% CI) | adjusted p-value |
| MTHFR | rs4845881 | G | 0.22 | 0.8 (0.6–1.1) | 0.13 | 0.59 | 1.1 (0.8–1.6) | 0.65 |
| rs7538516 | C | 0.3 | 0.8 (0.6–1.2) | 0.21 | 0.19 | 1.3 (0.9–1.8) | 0.25 | |
| rs4846040 | C | 0.31 | 0.8 (06–1.2) | 0.33 | 0.11 | 1.4 (0.9–2.0) | 0.10 | |
| rs2274976 | A | 0.31 | 0.7 (0.3–1.4) | 0.20 | 0.58 | 0.8 (0.5–1.5) | 0.55 | |
| rs13306556 | A | 0.95 | 1.0 (0.6–1.7) | 0.41 | 0.41 | 0.8 (0.5–1.4) | 0.38 | |
| rs12121543 | A | 0.98 | 1.0 (0.7–1.4) | 0.77 | 0.08 | 1.4 (1.0–2.0) | 0.11 | |
| rs6541003 | G | 0.61 | 0.9 (0.7–1.3) | 0.29 | 0.29 | 1.2 (0.8–1.7) | 0.35 | |
| rs1801133 | T | 0.75 | 0.9 (0.7–1.3) | 0.99 | 0.15 | 0.7 (0.5–1.1) | 0.16 | |
| rs9651118 | C | 0.59 | 1.1 (0.8–1.6) | 0.37 | 0.98 | 1.0 (0.7–1.4) | 0.88 | |
| rs2066470 | T | 0.98 | 1.0 (0.6–1.6) | 0.47 | 0.67 | 1.1 (0.6–2.1) | 0.84 | |
| MFRP | rs11217241 | T | 0.88 | 0.9 (0.5–1.9) | 0.31 | 0.31 | 0.8 (0.6–1.2) | 0.35 |
| rs948413 | A | 0.07 | 0.7 (0.5–1.0) | 0.24 | 0.18 | 0.8 (0.5–1.1) | 0.23 | |
| rs948414 | T | 0.02 | 0.7 (0.5–1.0) | 0.18 | 0.59 | 0.9 (0.6–1.3) | 0.56 | |
| rs35885438 | T | 0.91 | 1.0 (0.5–2.3) | 0.74 | 0.51 | 1.2 (0.7–1.9) | 0.44 | |
| rs10790289 | T | 0.55 | 0.9 (0.7–1.3) | 0.75 | 0.03 | 1.4 (1.0–2.0) | 0.06 | |
| rs12421909 | T | 0.21 | 1.5 (0.8–2.7) | 0.05 | 0.95 | 1.0 (0.7–1.4) | 0.98 | |
| rs2510143 | A | 0.24 | 1.6 (0.7–3.4) | 0.05 | 0.07 | 1.6 (0.9–2.7) | 0.08 | |
| rs36015759 | A | 0.02 | 0.6 (0.4–0.9) | 0.07 | 0.43 | 0.9 (0.6–1.3) | 0.40 | |
| rs883245 | C | 0.11 | 0.8 (0.6–1.1) | 0.46 | 0.23 | 1.2 (0.9–1.8) | 0.28 | |
| rs948415 | G | 0.29 | 0.8 (0.6–1.2) | 0.43 | 0.31 | 1.2 (0.8–1.7) | 0.37 | |
| rs3814759 | G | 0.33 | 0.9 (0.6–1.2) | 0.45 | 0.31 | 1.2 (0.8–1.7) | 0.37 | |
| CALCRL | rs840617 | A | 0.12 | 0.7 (0.4–1.1) | 0.79 | 0.26 | 1.2 (0.8–1.8) | 0.32 |
| rs13411274 | C | 0.36 | 1.2 (0.8–1.6) | 0.91 | 0.08 | 0.7 (0.4–1.1) | 0.07 | |
| rs6759535 | T | 0.58 | 0.9 (0.7–1.3) | 0.44 | 0.71 | 0.9 (0.7–1.3) | 0.63 | |
| rs6706141 | G | 0.45 | 1.1 (0.8–1.6) | 0.84 | 0.83 | 1.0 (0.7–1.5) | 0.70 | |
| rs3821183 | T | 0.68 | 0.9 (0.6–1.4) | 0.48 | 0.67 | 0.9 (0.6–1.3) | 0.69 | |
| rs9288141 | G | 0.69 | 1.1 (0.6–2.2) | 0.46 | 0.38 | 1.3 (0.7–2.2) | 0.48 | |
| rs3771073 | C | 0.73 | 1.1 (0.8–1.5) | 0.81 | 0.34 | 0.8 (0.6–1.2) | 0.33 | |
| rs2063505 | G | 0.66 | 1.1 (0.8–1.5) | 0.79 | 0.93 | 1.0 (0.7–1.5) | 0.85 | |
| rs7591567 | C | 0.53 | 1.1 (0.8–1.5) | 0.88 | 0.22 | 0.8 (0.5–1.2) | 0.20 | |