Figure 5 of Jiang, Mol Vis 2012; 18:2096-2106.


Figure 5. Effects of p38 mitogen-activated protein kinases (MAPK) inhibitor and nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) siRNA on nucleosome release. The apoptosis of retinal tissues was evaluated by nucleosome release ELISA. Eyes injected with SB203580 or NF-κB p65 siRNA had higher nucleosome release than the ischemia/reperfusion (I/R) control groups. Control: normal retinas, the other five groups were individually as I/R, I/R+vehicle (0.1% DMSO), I/R+control of siRNA in vehicle (Lipofectamine 2000 [Invitrogen] and DMEM/F12: no serum and no antibiotics), I/R+SB203580 and I/R+NF-κB siRNA. *Statistically significant compared to the I/R control: p<0.05. ** Statistically significant compared to the normal control: p<0.05. n=6 in each group. Cell number was given as mean±standard deviation (SD).