Table 2 of
Roshan, Mol Vis 2012; 18:181-193. Table 2 of
Roshan, Mol Vis 2012; 18:181-193.
Table 2. List of variations identified in healthy and cataract samples in relation to reference sequence (NC_012920).
| Locus | Nucleotide change | Amino acid change |
|---|---|---|
| 12S rRNA | A1438G | ——– |
| 16S rRNA | A1811G, A2706G, T2746C, Del3106C | ——– |
| ND1 | T3394C, A3397G, A3434G, G3483A, A3511G G3693A, T3847C, C3921A, T4023G, C4171T | Y30H, M31V, Y43C, E59E, T69A, L129L, L181L, S205S, T239T, L289L |
| T1 | T4291C | ——– |
| CO1 | C6452T, Ins6524A/T, C7028T, T7302C, T7319C | L183L, FmsftT207, A375A, L467L, I472I |
| ATP6 | A8679G, A8701G, T8843C, A8860G, A9135G | K51K, T59A, I106T, T112A, E203E |
| CO3 | T9540C, A9632C | L112L, V142V |
| TG | T10031C | ——– |
| ND3 | A10398T, C10400T | T114S, T114T |
| ND4L | G10685A | A72A |
| ND4 | C10797T, T10873C, A11467G, G11719A, G12007A | P13L, P38P, L236L, G320G, W416W |
| tRNA | A12308G | ——– |
| ND5 | G12372A, A12999G, C13668T, A13956C, C14109T | L12L, A221A, N444N, L540L, F591F |
| ND6 | G12501A | M55M |
| ND5 | T12696C, C12705T, A12999G, C13668T, C13943T, A13956C, C14109T | Y120Y, I123I, A221A, N444N, T536M, L540L, F591F |
| ND6 | C14155T | G173G |
| Cytb | C14766T, T14783C, G14905A, G15043A, T15155C, A15133G, G15301A, A15326G | T7I, L13L, M53M, G99G, T123T, M129M, L185L, T194A |
| D-loop | A93G, A153G, T152C, A73G, G66T, Ins65T, Del58T, Del57T, Ins55T, A16206C, C16223T, T16311C, T16445C, T16519C, C16527T | ——– |