Figure 5. In vitro hexadecyloxypropyl
cytarabine 3’,5’-cyclic monophosphate (HDP-cP-Ara-C) release
profile. HDP-cP-Ara-C had a peak release around day 10, and the
compound was still detectable at the end of the experiment (day
36). HDP-cP-Ara-C and hexadecyloxypropyl cytarabine
5’-monophosphate (HDP-P-Ara-C) were detected in the dissolution
chamber eluate.