Table 3 of
Yang, Mol Vis 2012; 18:1865-1873. Table 3 of
Yang, Mol Vis 2012; 18:1865-1873.
Table 3. Comparison of genotype and allele frequencies of rs800292, rs4505848, and rs4788084 polymorphisms in subgroups of noninfectious uveitis and control subjects.
| Polymorphism | BD (n=19) | IU (n=38) | VKH (n=38) | Controls (n=308) | pBD-C | pIU-C | pVKH- C |
|---|---|---|---|---|---|---|---|
| rs800292 (CFH 184G/A) | |||||||
| Genotype | |||||||
| AA | 0 (0) | 3 (7.9) | 3 (7.9) | 48 (15.6) | NS | NS | NS |
| AG | 12 (63.2) | 19 (50.0) | 18 (47.4) | 145 (47.1) | |||
| GG | 7 (36.8) | 16 (42.1) | 17 (44.7) | 115 (37.3) | |||
| Allele | |||||||
| A | 12 (31.6) | 25 (32.9) | 24 (31.6) | 241 (39.1) | NS | NS | NS |
| G | 26 (68.4) | 51 (67.1) | 52 (68.4) | 375 (60.9) | |||
| rs4505848 (KIAA1109 A/G) | |||||||
| Genotype | |||||||
| GG | 7 (36.8) | 3 (7.9) | 7 (18.4) | 50 (16.2) | 0.028§ | NS | NS |
| AG | 10 (52.6) | 20 (52.6) | 23 (60.5) | 157 (51.0) | 0.043† | ||
| AA | 2 (10.5) | 15 (39.5) | 8(21.1) | 101 (32.8) | 0.031‡* | ||
| Allele | |||||||
| G | 24 (63.2) | 26 (34.2) | 37 (48.6) | 257 (41.7) | 0.01 | NS | NS |
| A | 14 (36.8) | 50 (65.8) | 39 (51.4) | 359 (58.3) | |||
| rs4788084 (IL27 C/T) | |||||||
| Genotype | |||||||
| TT | 1 (5.3) | 4 (10.5) | 3 (7.9) | 21 (6.8) | NS | NS | NS |
| CT | 9 (47.4) | 14 (36.8) | 13 (34.2) | 126 (40.9) | |||
| CC | 9 (47.4) | 20 (52.6) | 22 (57.9) | 161 (52.3) | |||
| Allele | |||||||
| T | 11 (28.9) | 22 (28.9) | 19 (25.0) | 168 (27.3) | NS | NS | NS |
| C | 27 (61.1) | 54 (71.1) | 57 (75.0) | 448 (72.7) | |||