Figure 3. The effect of Y-27632 on fibroblast contractility. A: TGFβ1 induced collagen contraction over time. Y-27632-application significantly inhibited the contraction of fibroblast-seeded collagen gels. B: Statistical analysis of the area of collagen gels by ImageJ software. Values are means±SEM (n=3). *p<0.01 (Student’s t-test).