Table 4 of
Chen, Mol Vis 2012; 18:1629-1639. Table 4 of
Chen, Mol Vis 2012; 18:1629-1639.
| rs1533428 (dominant) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| TT + CT (%) | CC (%) | ||||||||
| SNP | Genotype(s) | POAG | Control | p-value | Odds ratio (95% CI) | POAG | Control | p-value | Odds ratio (95% CI) |
| Hong Kong cohort | |||||||||
| rs7037117 | GG | 8 (4.3) | 5 (2.2) | 0.077 | 2.91 (0.90–9.37) | 6 (3.3) | 3 (1.3) | 0.080 | 3.63 (0.87–15.17) |
| (recessive) | AG + AA | 121 (65.8) | 132 (57.6) | 0.019 | 1.67 (1.09–2.55) | 49 (26.6) | 89 (38.9) | 1.0 | 1.0 |
| Shantou cohort | |||||||||
| rs7037117 | GG | 11 (10.8) | 3 (2.1) | 0.0010 | 7.61 (1.93–29.53) | 4 (3.9) | 4 (2.7) | 0.44 | 2.07 (0.48–8.93) |
| (recessive) | AG + AA | 60 (58.8) | 83 (56.8) | 0.16 | 1.50 (0.85–2.64) | 27 (26.5) | 56 (38.4) | 1.0 | 1.0 |
| Combined cohort | |||||||||
| rs7037117 | GG | 19 (6.6) | 8 (2.1) | 0.00028 | 4.53 (1.90–10.83) | 10 (3.5) | 7 (1.9) | 0.043 | 2.73 (1.0–7.45) |
| (recessive) | AG + AA | 181 (63.3) | 215 (57.3) | 0.0063 | 1.61 (1.14–2.26) | 76 (26.6) | 145 (38.7) | 1.0 | 1.0 |