Figure 7. Effect of treatment with 9-cis-retinal for the expression of photoreceptor specific genes in Rpe65^−/− mice at three weeks. Semiquantitative real-time RT–PCR was performed to determine transcriptional levels of M-opsin (A), S-opsin (B), GNAT2 (C), rhodopsin (D), and GNAT1 (E). No significant change in the transcriptional levels of five genes was present between 0.5 nM 9-cis-retinal treatment and vehicle treatment for 12 h. Values represent mean±SD (n=6).