Figure 7. Effect of treatment with 9-cis-retinal
for the expression of photoreceptor specific genes in Rpe65−/−
mice at three weeks. Semiquantitative real-time RT–PCR was
performed to determine transcriptional levels of M-opsin (A),
S-opsin (B), GNAT2 (C), rhodopsin (D),
and GNAT1 (E). No significant change in the
transcriptional levels of five genes was present between 0.5 nM
9-cis-retinal treatment and vehicle treatment for 12 h.
Values represent mean±SD (n=6).