Effect of fumonisin B1 on the palmitate-induced IL-6 and MCP-1 secretion from orbital fibroblasts. Orbital fibroblasts were
pretreated with fuminosin B1 (10 μM) for 1 h, followed by treatment with palmitate (200 μM) for 24 h. Concentrations of IL-6
) and MCP-1 (B
) were determined by ELISA. Data are presented as the mean±SD of three replicate culture wells from a representative experiment.
Similar results were observed in three independent experiments using orbital fibroblasts from #1 patient with TAO (Table 1
). * p<0.05.