Figure 3 of Mohamed, Mol Vis 2012; 18:1457-1466.


Figure 3. Early stage hypertension and diabetes suppress the Akt survival pathway. A: Representative image for western blot analysis of retinal phosphorylated-AKt (AKt) protein expression in early stage spontaneous hypertensive rats (SHR) and diabetic spontaneous hypertensive rats (SHR+D) compared to control wistar group (W). B: Statistical analysis showing that activation of pAkt was inhibited by 0.5 fold in the SHR group that was increased to 0.7 fold in the combined SHR+D group relative to the control W group (n=3-4, *p<0.05).