Table 2 of Mitra, Mol Vis 2012; 18:1361-1378.


Table 2. Comparison of IC50 values of respective native drugs and drug loaded nanoparticles between Y79 cells co-cultured with microparticles (3-D0 and Y79 cells cultured without microparticles (2-D).

  IC50  
Drug 2-D 3-D Fold change
Native doxorubicin 154.8 1202 7.76
Np doxorubicin 9.54 102.3 10.7
Native etoposide 17.66 159.2 9.01
Np etoposide 3.86 17.37 4.5
Native carboplatin 138 1584 11.47
Np carboplatin 28.84 630 21.84