Table 2 of
Mitra, Mol Vis 2012; 18:1361-1378. Table 2 of
Mitra, Mol Vis 2012; 18:1361-1378.
Table 2. Comparison of IC50 values of respective native drugs and drug loaded nanoparticles between Y79 cells co-cultured with microparticles (3-D0 and Y79 cells cultured without microparticles (2-D).
| IC50 | |||
|---|---|---|---|
| Drug | 2-D | 3-D | Fold change |
| Native doxorubicin | 154.8 | 1202 | 7.76 |
| Np doxorubicin | 9.54 | 102.3 | 10.7 |
| Native etoposide | 17.66 | 159.2 | 9.01 |
| Np etoposide | 3.86 | 17.37 | 4.5 |
| Native carboplatin | 138 | 1584 | 11.47 |
| Np carboplatin | 28.84 | 630 | 21.84 |